Vaccine for the prevention of influenza GC FLU, №10
Immunological and biological properties.
The GC Flu Quadrivalent vaccine is prepared from virus grown in the allantoic cavity of chicken embryos, inactivated with formaldehyde, and then diluted in saline with phosphate buffer to the desired concentration. The strain composition of viral antigens contained in the GC Flu Quadrivalent vaccine is in line with WHO guidelines for the 2021-2022 season. The GC Flu Quadrivalent vaccine causes the formation of antibodies and protects against the clinical manifestations of the disease through vaccination. Because the influenza virus is variable and its antigenic properties change significantly from time to time, the protection afforded by the GC Flu Quadrivalent vaccine is limited to the strains from which the vaccine is made or to closely related strains. In general, seroprotection is achieved within 2-3 weeks. The duration of immunity after vaccination depends on the vaccine strain and usually lasts from 6 to 12 months.
Composition of the substance
1 pre-filled syringe 0.5 ml:
Active substances: purified inactivated influenza viruses 60 μg: purified inactivated influenza type A viral antigen [A / Victoria / 2570/2019 (H1N1) pdm09-shaped – A / Victoria / 2570/2019 IVR-215] 15 μg purified inactivated influenza type A viral antigen [ A / Cambodia / e0826360 / 2020 (H3N2) -shaped – A / Cambodia / e0826360 / 2020 IVR-224] 15 μg purified inactivated influenza type B viral antigen [B / Washington / 02/2019 (B / Victoria line) -shaped – B / Washington / 02/2019] 15 μg purified inactivated influenza type B viral antigen [B / Phuket / 3073/2013 (B / Yamagata line) -shaped – B / Phuket / 3073/2013] 15 μg.
Excipients: sodium chloride 4 mg; potassium chloride 0,1 mg; Disodium hydrogen phosphate dihydrate 0.6 mg; potassium dihydrophosphate 0.1 mg; water for injections to 0.5 ml.
Medicinal form. Suspension for injection.
Basic physicochemical properties: Colorless but slightly whitish liquid.
Pharmacotherapeutic group. Vaccine for the prevention of influenza. Code ATX J07B B02